Synonyms |
Zonegran |
SPECIMEN REQUIREMENTS |
|
Container Type |
Red top tube (plain) |
Supply Item Number |
1372 |
Specimen Type |
Serum |
Preferred Volume |
1.5 mL |
Emergency Minimum Volume |
0.8 mL |
Patient Prep |
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. |
Specimen Processing |
Separate serum or plasma from cells ASAP or within 2 hours of collection and transfer to a standard PAML aliquot tube. |
Store and Transport |
Refrigerated |
Stability |
Room Temp 1 week Refrigerated 1 week Frozen (-20 °C) 1 month |
Unacceptable Condition |
Whole blood; serum or plasma separator tubes; grossly hemolyzed specimens |
Alternate Specimens |
Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin) |
Limitations |
If testing is to be delayed by more than 1 week, specimens should be stored frozen for up to 1 month prior to being tested. Avoid repeated freezing and thawing of the specimen. |
Reference Laboratory |
PAML |
CPT Codes |
80203 |
Interface Order Code |
80299.Z53 |
Billing Code |
ZONI |
Test Schedule |
Mon-Fri |
Turnaround Time |
1-3 days |
Method |
PETIA |
Reference Ranges |
Title | Ranges | Units | Zonisamide | 10.0-40.0 | ug/mL | The proposed therapeutic range for seizure control is 10.0-40.0 ug/mL. Concentrations that exceed 80.0 ug/mL, may contribute to adverse effects. | Pharmacokinetics varies widely, particularly with co-medications and/or compromised renal function. |
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