| Synonyms | Aventyl; Pamelor |
| SPECIMEN REQUIREMENTS | |
| Container Type | Red top tube (plain) |
| Supply Item Number | 1372 |
| Specimen Type | Serum |
| Preferred Volume | 0.5 mL |
| Emergency Minimum Volume | 0.2 mL |
| Collection Procedure | Optimal time to collect sample: Draw 10-14 hours post-dose. If a divided dose is given, draw before morning dose. |
| Specimen Processing | Blood samples should be collected by venipuncture in a plain red top and serum samples must be allowed to clot naturally at room temperature. Separate serum from cells within 4 hours and place in separate polypropylene (not polystyrene) tube. |
| Store and Transport | Refrigerated
|
| Required Patient Info | Date and time of dose and draw |
| Stability | Room Temp 5 days Refrigerated 1 week Frozen (-20 °C) 1 month Frozen (-70 °C) 1 year |
| Unacceptable Condition | DO NOT use gel separator tubes (Corvac®, SST or equivalent) for the collection of blood samples for this test. |
| Limitations | Protriptyline interferes with nortriptyline. |
| Reference Laboratory | PAML |
| Reference Lab Test Code | LCA code 911154 |
| CPT Codes | 80335, (HCPCS G0480) |
| Interface Order Code | 80182 |
| Billing Code | NOR |
| Test Schedule | Mon, Wed, Fri |
| Turnaround Time | 1-3 days |
| Method | Tandem Mass Spectrometry |
| Reference Ranges | | Title | Descriptor | Ranges | Units | | Nortriptyline | Therapeutic | 50-150 | ng/mL | | Toxic | > 150 |
|
| Compliance Remarks | This test was developed and its performance characteristics determined by PAML. The U.S. Food and Drug Administration (FDA) has not approved or cleared this test. However, FDA approval or clearance is currently not required for clinical use of this test. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. PAML is authorized under Clinical Laboratory Improvement Amendments (CLIA) to perform high-complexity testing. |
