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Test Code
This test is a lab developed test. For further information, see the Compliance Remarks section below.
SynonymsElavil; Endep; Etrafon; Triavil, Desipramine
Container TypeRed top tube (plain)
Supply Item Number1372
Specimen TypeSerum
Preferred Volume0.5 mL
Emergency Minimum Volume0.2 mL
Collection ProcedureOptimal time to collect sample: Draw 10-14 hours post-dose. If a divided dose is given, draw before morning dose.
Specimen ProcessingBlood samples should be collected by venipuncture in a plain red top and serum samples must be allowed to clot naturally at room temperature. Separate serum from cells within 4 hours and place in separate polypropylene (not polystyrene) tube.
Store and TransportRefrigerated
Required Patient InfoDate and time of dose and draw.
StabilityRoom Temp 5 days  Refrigerated 1 week  Frozen (-20 °C) 1 month  Frozen (-70 °C) 1 year  
Unacceptable ConditionDO NOT use gel separator tubes (Corvac®, SST or equivalent) for the collection of blood samples for this test.
Reference LaboratoryPAML
Reference Lab Test CodeLCA code 911148
CPT Codes80335, (HCPCS G0480)
Interface Order Code80174
Billing CodeIMI
Test ScheduleMon, Wed, Fri
Turnaround Time1-3 days
MethodTandem Mass Spectrometry
Reference Ranges
ImipramineNot Established ng/mL
DesipramineNot Established ng/mL
Total (Imipramine + Desipramine)100-300ng/mL
Compliance RemarksThis test was developed and its performance characteristics determined by PAML. The U.S. Food and Drug Administration (FDA) has not approved or cleared this test. However, FDA approval or clearance is currently not required for clinical use of this test. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. PAML is authorized under Clinical Laboratory Improvement Amendments (CLIA) to perform high-complexity testing.

Interface Codes
typeorder codetest descriptionresult coderesult descriptionunitsdecimal placesloinc code
o80174Imipramine and Metabolite
r80174Imipramine and Metabolite80160Desipramineng/mL03531-1
r80174Imipramine and Metabolite80174.Z1Imipramineng/mL03690-5
r80174Imipramine and Metabolite80174.Z3Total Imip+Desipng/mL09627-1