| Synonyms | Zonegran |
| SPECIMEN REQUIREMENTS | |
| Container Type | Red top tube (plain) |
| Supply Item Number | 1372 |
| Specimen Type | Serum |
| Preferred Volume | 1.5 mL |
| Emergency Minimum Volume | 0.8 mL |
| Patient Prep | Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. |
| Specimen Processing | Separate serum or plasma from cells ASAP or within 2 hours of collection and transfer to a standard PAML aliquot tube. |
| Store and Transport | Refrigerated |
| Stability | Room Temp 1 week Refrigerated 1 week Frozen (-20 °C) 1 month |
| Unacceptable Condition | Whole blood; serum or plasma separator tubes; grossly hemolyzed specimens |
| Alternate Specimens | Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin) |
| Limitations | If testing is to be delayed by more than 1 week, specimens should be stored frozen for up to 1 month prior to being tested. Avoid repeated freezing and thawing of the specimen. |
| Reference Laboratory | PAML |
| CPT Codes | 80203 |
| Interface Order Code | 80299.Z53 |
| Billing Code | ZONI |
| Test Schedule | Mon-Fri |
| Turnaround Time | 1-3 days |
| Method | PETIA |
| Reference Ranges | | Title | Ranges | Units | | Zonisamide | 10.0-40.0 | ug/mL | | The proposed therapeutic range for seizure control is 10.0-40.0 ug/mL. Concentrations that exceed 80.0 ug/mL, may contribute to adverse effects. | | Pharmacokinetics varies widely, particularly with co-medications and/or compromised renal function. |
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